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In recent years, increasing numbers of adult patients have sought orthodontic treatment and expressed a desire for esthetic and comfortable alternatives to conventional fixed appliances. The possibility of using clear overlay orthodontic appliances was introduced in 1946, when Kesling devised the concept of using a series of thermoplastic tooth positioners to progres- sively move misaligned teeth to improved positions. In 1997, Align TechnologyG (Santa Clara, Calif) adapted and incorporated modern technologies to introduce the clear aligner treatment (CAT) as we know it, rendering Kesling’s concept a feasible orthodontic treatment option. Although CAT has been cited as a safe, esthetic, and comfortable orthodontic procedure for adult patients, only a few investigations have focused on the predictability of orthodontic tooth movement (OTM).