Остання редакція: 2017-03-15
Аннотація
Repolarization abnormalities on surface-ECG are well-known indicators and predictors of unfavorable clinical outcomes in coronary arteries disease (CAD). Surface ECG presents only limited and non-specific data of repolarization changes provoked by myocardial ischemia. Visualization of dynamic ECG-trackers in phase-oriented space during 6-minutes walking test provides additional accurate information about repolarization abnormalities.
Aim of the study. To evaluate the additional diagnostic possibilities of phase-shaped ECG analysis in stress-testing of patients with ischemic heart failure.
Methods. Index of T-wave symmetry, T-wave dispersion, βT index and QRS/T spaces ratio were analyzed. Simultaneous recordings of surface ECG were also performed.
Results. 212 patients were enrolled to the study. Index of T-wave symmetry and βT index haven´t shown any beneficial results of sensitivity (73% vs. 81%; p≥0.05) and specificity (78% vs. 69%; p≥0.05) comparing with typical signs of ischemia on surface ECG (ST-segment deviation and/or T-wave changes). T-wave dispersion resulted in higher levels of sensitivity (82% vs. 64%; p≤0.05) but not specificity (72% vs. 67%; p≥0.05) as well, as QRS/T spaces ratio: sensitivity (76% vs. 58%; p≤0.05) and specificity (68% vs. 71%; p≥0.05). The lowering of QRS/T spaces ratio (cut-point is ≥10%) correlated with the distance covered in 6-minutes walking test (rs=0.682; p≤0.05).
Conclusions. T-wave dispersion and QRS/T spaces ratio of phase-shaped ECGs are useful in detecting repolarization abnormalities in stress-testing due to their higher sensitivity.